6533b7ddfe1ef96bd127490f

RESEARCH PRODUCT

Pulmonary cytomegalovirus (CMV) DNA shedding in allogeneic hematopoietic stem cell transplant recipients: Implications for the diagnosis of CMV pneumonia

Juan MontoroAitana Balaguer-rosellóPaula MolesMiguel SalavertEstela GiménezVíctor VinuesaDavid NavarroPaula AmatCarlos CarreteroMaría Dolores GómezCarlos SolanoJaime SanzAriadna PérezJosé Luis PiñanaGuillermo SanzJuan Carlos Hernández-boludaEva GonzalezMar Tormo

subject

Male0301 basic medicineDna loadCMV pneumoniaCytomegalovirusmedicine.disease_causechemistry.chemical_compound0302 clinical medicinePre-emptive antiviral therapyMedicine030212 general & internal medicineCMV DNA in BALAged 80 and overmedicine.diagnostic_testHematopoietic Stem Cell Transplantationvirus diseasesrespiratory systemMiddle AgedViral LoadVirus SheddingInfectious DiseasesCytomegalovirus InfectionsFemaleAllogeneic hematopoietic stem cell transplantBronchoalveolar Lavage FluidAdultMicrobiology (medical)Pneumonia Viral030106 microbiologyCMV DNAemiaArticle03 medical and health sciencesHumansTransplantation HomologousAgedRetrospective Studiesbusiness.industryCMV PneumoniaCytomegalovirusRetrospective cohort studymedicine.diseaseTransplant Recipientsrespiratory tract diseasesPneumoniaBronchoalveolar lavagechemistryDNA ViralImmunologybusinessDNA

description

Highlights • CMV DNA is frequently detected in BAL fluid specimens from allo-HSCT. • CMV DNA detection in BAL fluids is comparable across pneumonia etiologies. • CMV DNA loads in BAL fluids are comparable across pneumonia etiologies. • CMV DNA load in BAL may predict attributable-pneumonia mortality.

https://doi.org/10.1016/j.jinf.2019.02.009