Addition reactions of azoesters with 2-thioquinazolinones

6533b7ddfe1ef96bd1275125

RESEARCH PRODUCT

Addition reactions of azoesters with 2-thioquinazolinones

Gaetano Giammona Bianca Carlisi Salvatore Palazzo Libera Italo Giannola

subject

Turn (biochemistry)Inert Diethyl azodicarboxylate Solvent Addition reaction chemistry.chemical_compound Thiourea Chemistry Organic Chemistry Organic chemistry Mass spectrometry

description

Reaction between diethyl azodicarboxylate (I) and 1,2,3,4-tetrahydro-2-thioquinazolin-4-one (II), as a cyclic model of thiourea, both in alcoholic medium and in inert solvents has been investigated. By carrying out the reaction in an inert solvent, it was possible to isolate an intermediate. Evidence is presented that the intermediate, in turn, was converted into the final products. Structures were unequivocally assigned by mass spectrometry.

year	journal	country	edition	language
1981-12-01	Journal of Heterocyclic Chemistry

https://doi.org/10.1002/jhet.5570180814

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