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RESEARCH PRODUCT

Assembling a consensus on actinic cheilitis: A Delphi study.

Javier Seoane-romeroMiguel ÁNgel González-molesSaman WarnakulasuriyaManuel Pereiro-ferreirósJosé Manuel Aguirre-urizarPablo Varela-centellesGonzalo Hernández-vallejoJose V. BaganJuan SeoanePía López-jornet

subject

Cancer Researchmedicine.medical_specialtyConsensusDelphi TechniqueetiologyefficacyDelphi methodPalpationPathology and Forensic Medicinelip03 medical and health sciences0302 clinical medicinepotentially malignant disordersInternal medicineSurveys and QuestionnairesBiopsymedicineactinic cheilitisHumansResponse rate (survey)CO2-lasermedicine.diagnostic_testbusiness.industryActinic cheilitis030206 dentistrymedicine.diseasepotentially malignant oral disorderDelphi studyOtorhinolaryngologyphotodynamic therapyCheilitisHomogeneousconsensus030220 oncology & carcinogenesiskeratosisPeriodonticsOral Surgerybusiness

description

Aims: To discuss the terminology to define and classify actinic cheilitis (AC) and to build a consensus on the diagnostic and therapeutic approaches to AC. Methods: Two-round Delphi study using a questionnaire including 34 closed sentences (9 on terminology and taxonomy, 5 on potential for malignant transformation, 12 on diagnostic aspects, 8 on treatment) and 8 open questions. Experts’ agreement was rated using a Likert scale (1–7). Results: A consensus was reached on 24 out 34 statements (73.5%) and on 5 out of 8 (62.5%) close-ended questions. The response rate was identical in both rounds (attrition of 0%). AC is the term with the highest agreement (median of 7 (strongly agree; IQR: 6–7)) and the lowest dispersion (VC = 21.33). ‘Potentially malignant disorder’ was the preferred classification group for AC (median of 7) and 85.6% of participants showing some level of agreement (CV < 50). Experts (66.75%) consider AC a clinical term (median: 7; IQR: 4–7) and believe definitive diagnosis can be made clinically (median: 6; IQR: 5–7), particularly by inspection and palpation (median: 5; IQR: 4–6). Histopathological confirmation is mandatory for the management of AC (median: 5; IQR: 2.5–7), even for homogeneous lesions (median: 5; IQR: 3.5–6). Consensus was reached on all treatment statements (VC < 50). Conclusions: AC is a potentially malignant disorder with a significant lack of agreement on diagnostic criteria, procedures, biopsy indications and the importance of techniques to assist in biopsy. A consensus was reached on nomenclature and management of this disorder SI

yearjournalcountryeditionlanguage
2021-06-09Journal of oral pathologymedicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral PathologyREFERENCES
10.1111/jop.13200https://pubmed.ncbi.nlm.nih.gov/33998055