Acetylcholinesterase-Capped Mesoporous Silica Nanoparticles That Open in the Presence of Diisopropylfluorophosphate (a Sarin or Soman Simulant)

6533b7defe1ef96bd1275d54

RESEARCH PRODUCT

Acetylcholinesterase-Capped Mesoporous Silica Nanoparticles That Open in the Presence of Diisopropylfluorophosphate (a Sarin or Soman Simulant)

Lluís Pascual Félix Sancenón Ana M. Costero Ana M. Costero Salvador Gil Salvador Gil Pablo Gaviña Pablo Gaviña Ramón Martínez-máñez Sameh El Sayed

subject

NANOCAPSULES RESPONSIVE CONTROLLED-RELEASE Sarin GATED MATERIALS Nanoparticle 02 engineering and technology CHEMICAL WARFARE AGENTS 010402 general chemistry 01 natural sciences Biochemistry Nanocapsules chemistry.chemical_compound QUIMICA ORGANICA DESIGN Soman medicine Rhodamine B Organic chemistry DRUG-DELIVERY Physical and Theoretical Chemistry Nerve agent NANOCONTAINERS Chemistry QUIMICA INORGANICA Organic Chemistry DNA Mesoporous silica 021001 nanoscience & nanotechnology GUEST MOLECULES 0104 chemical sciences Diisopropyl fluorophosphate DCNP 0210 nano-technology medicine.drug Nuclear chemistry

description

Mesoporous silica nanoparticles loaded with rhodamine B and capped with acetylcholinesterase are able to be selectively opened and deliver their cargo in the presence of nerve agent simulant diisopropyl fluorophosphate (DFP).

year	journal	country	edition	language
2016-10-18	Organic Letters

https://doi.org/10.1021/acs.orglett.6b02793

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