6533b7defe1ef96bd127680e

RESEARCH PRODUCT

Model-Based Dose Calculation Algorithms for Brachytherapy Dosimetry

Javier VijandeMark J. RivardShirin A. EngerShirin A. Enger

subject

MaleCancer ResearchDose calculationmedicine.medical_treatmentBrachytherapyBrachytherapyDose distribution030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineNeoplasmsmedicineHumansDosimetryRadiology Nuclear Medicine and imagingRadiometryHead and neckSocieties MedicalPhotonsTask groupbusiness.industryRadiotherapy Planning Computer-AssistedRadiotherapy DosageModels Theoretical3. Good healthFormalism (philosophy of mathematics)Oncology030220 oncology & carcinogenesisPractice Guidelines as TopicFemalebusinessAlgorithmAlgorithms

description

The purpose of this study was to review the limitations of dose calculation formalisms for photon-emitting brachytherapy sources based on the American Association of Physicists in Medicine (AAPM) Task Group No. 43 (TG-43) report and to provide recommendations to transition to model-based dose calculation algorithms. Additionally, an overview of these algorithms and approaches is presented. The influence of tissue and seed/applicator heterogeneities on brachytherapy dose distributions for breast, gynecologic, head and neck, rectum, and prostate cancers as well as eye plaques and electronic brachytherapy treatments were investigated by comparing dose calculations based on the TG-43 formalism and model-based dose calculation algorithms.

yearjournalcountryeditionlanguage
2019-11-16Seminars in Radiation Oncology
https://doi.org/10.1016/j.semradonc.2019.08.006