6533b81ffe1ef96bd1276e4d

RESEARCH PRODUCT

Induction des mécanismes de défense des plantes : Les acquis du modèle tabac/cryptogéine

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description

Cryptogein is a small protein secreted by the oomycete Phytophthora cryptogea, able to trigger on tobacco plants both the developmenl of an hypersensitive response and the induction of resistance against a wide range of pathogens. The deciphering of molecular events associated with this process, using tobacco as a model plant, gave significant informations about the set up of defense mechanisms. The role of plasma membrane dynamics in such a signal transduction has been evidenced. ln particular; the presence of plasma membrane microdomains concentrating signaling proteins, and the modification of the proteic content of these domains upon cryptogein treatment have been demonstrated. Moreover; cell biology approaches revealed that cryptogein induced a rapid and transient invagination of plasma membrane, leading to the formation and internalization of clathrin-coated endocytic vesicles. Our present project aims at studying the role of such a process in the set up of defense signal transduction triggered by cryptogein.