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RESEARCH PRODUCT

Next-Generation Genomic Profiling of Hepatocellular Adenomas: A New Era of Individualized Patient Care

Snorri S. ThorgeirssonJens U. Marquardt

subject

Cancer Researchmedicine.medical_specialtyCarcinoma HepatocellularGenomic profilingAdenomaMEDLINEBiologyBioinformaticsPatient careAdenoma Liver CellText miningInternal medicinemedicineCarcinomaAnimalsHumansbusiness.industryLiver NeoplasmsCell BiologyProtein-Tyrosine Kinasesmedicine.diseaseOmicsdigestive system diseasesNeoplasm ProteinsCell Transformation NeoplasticEndocrinologyOncologyCancer cellbusiness

description

Hepatocellular adenomas (HCAs) are clinically relevant benign liver lesions that commonly occur in women on hormonal contraceptives. In this issue of Cancer Cell, Pilati and colleagues present an integrative multi-“omics”-based analysis of HCA and identify recurrent genetic alterations associated with adenoma-carcinoma transition and new drugable targets.

yearjournalcountryeditionlanguage
2014-04-01Cancer Cell
https://doi.org/10.1016/j.ccr.2014.03.032