6533b820fe1ef96bd127a387
RESEARCH PRODUCT
Die Hemmung der Aufnahme vonα-Methylnoradrenalin in das Herz durch sympathomimetische Amine
Erich MuschollE. Webersubject
PharmacologyPerfusion fluidChromatographyStereochemistryChemistryPharmacology toxicologyTyrode solutionAmine gas treatingGeneral Medicinedescription
Hearts of rabbits were isolated and perfused with Tyrode solution containing 10 ng/ml (−)-α-methyl noradrenaline. The uptake by the heart ofα-methyl-noradrenaline was calculated by estimating the amount of amine removed from the perfusion fluid while passing through the heart. In control experiments the mean removal ofα-methyl noradrenaline was 43,7 ± 1,6% of the amount infused. The rate of removal remained constant throughout the time period of the experiment, i.e. 20 min.
year | journal | country | edition | language |
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1965-11-01 | Naunyn-Schmiedebergs Archiv für Experimentelle Pathologie und Pharmakologie |