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RESEARCH PRODUCT
Containment of a Large SARS-CoV-2 Outbreak Among Healthcare Workers in a Pediatric Intensive Care Unit.
Rebecca Luise KnollFrank KowalzikMaximiliano Luis CacicedoStephan GehringFred ZeppGloria BonewitzK. WeiseJulia WinterBodo PlachterKatja HilbertBritta GröndahlWolfgang KohnenWalter E. HitzlerStefan RunkelJonas Kloppsubject
Microbiology (medical)AdultMalemedicine.medical_specialtyInfectious Disease Transmission Patient-to-ProfessionalSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Health PersonnelPneumonia ViralPsychological interventionIntensive Care Units PediatricHospitals UniversityTertiary Care Centers03 medical and health sciencesBetacoronavirusYoung Adult0302 clinical medicine030225 pediatricsIntensive careGermanyPandemicHealth caremedicineInfection controlHumansPediatrics Perinatology and Child Health030212 general & internal medicinePandemicsPediatric intensive care unitInfection Controlbusiness.industrySARS-CoV-2virus diseasesOutbreakCOVID-19Middle AgedInfectious DiseasesPediatrics Perinatology and Child HealthEmergency medicineQuarantineFemalebusinessCoronavirus Infectionsdescription
Objective Healthcare workers (HCWs) are particularly exposed SARS-CoV-2 because they are critical in preventing viral transmission and treating COVID-19 patients. Within HCWs, personnel of intensive care units (ICUs) are at the forefront of treating patients with a severe course of COVID-19 infection and therefore represent an extremely vulnerable group. Thus, our objective is to contribute to establish means of infection control protecting HCWs in the frontline of the current pandemic. Design An outbreak of SARS-CoV-2 was detected and contained in a pediatric ICU (PICU). The first positive case was identified with a point-of-care diagnostic system on site. Real-time PCR-based testing systems from self-collected nasopharyngeal samples swabs were used to test for viral RNA of SARS-CoV-2 in the follow-up. Setting PICU within a tertiary university hospital in Germany. Participants Healthcare workers of the PICU. Interventions Positive HCWs were sent into quarantine. Containment measures were implemented including wearing of surgical-masks, physical distancing and systematic testing. Results Among 432 HCWs, 91 (25%) were tested. Forty-five percent reported symptoms corresponding to characteristics of COVID-19. Of those, only 19,5% (8 HCWs) were tested positive for SARS-CoV-2. No infection occurred outside the PICU. After the implementation of containment measures, viral transmission was stopped. Conclusions In the present study, a large outbreak within a team of healthcare workers of a PICU, affecting almost one fifth of the entire personnel is documented, along with detailed insights about how the outbreak was contained and how operability of the unit was maintained.
year | journal | country | edition | language |
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2020-08-22 | The Pediatric infectious disease journal |