Novel therapeutic targets in esophageal cancer: impact of chemokine receptor CXCR4

6533b821fe1ef96bd127aecf

RESEARCH PRODUCT

Novel therapeutic targets in esophageal cancer: impact of chemokine receptor CXCR4

Markus Moehler Ines Gockel Theodor Junginger Carl C. Schimanski

subject

Receptors CXCR4 Cancer Research Esophageal Neoplasms business.industry Antineoplastic Agents General Medicine Esophageal cancer medicine.disease CXCR4 Chemokine CXCL12 Cyclin-Dependent Kinases Neoadjuvant Therapy humanities Chemokine receptor Drug Delivery Systems Oncology Cancer research medicine Humans Malignant cells business Chemokines CXC Homing (hematopoietic)

description

Ines Gockel†, Carl C Schimanski, Markus Moehler & Theodor Junginger †Author for correspondence Johannes GutenbergUniversity of Mainz, Department of General and Abdominal Surgery, Langenbeckstr. 1, 55131 Mainz, Germany Tel.: +49 6131 177 291; Fax: +49 6131 176 630; gockel@ach.klinik.unimainz.de ‘The interaction between esophageal cancer-expressed CXCR4 and SDF-1α may have a key role in directing malignant cells to ‘homing’ organs ... thus, this mechanism may account for metastasis.’

year	journal	country	edition	language
2007-04-01	Future Oncology

https://doi.org/10.2217/14796694.3.2.119

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