6533b821fe1ef96bd127b76e
RESEARCH PRODUCT
Radial Scar Versus Tubular Carcinoma of the Breast
Robert C. CallaghanA. Ruiz-sauríJuan Carlos CalderónS. Almenar-medinaAntonio Llombart-boschsubject
Pathologymedicine.medical_specialtymedicine.diagnostic_testRadial scarNuclear areaTubular CarcinomasCell BiologyBiologymedicine.diseasePathology and Forensic MedicineFlow cytometryStromamedicineImage CytometryTubular carcinomaDifferential diagnosisdescription
Summary The present study is focused on the differential diagnosis between radial scar (RS) and tubular carcinoma (TC) using morphometrical and cytophotometrical analysis (static and flow cytometry) of a number of histologically well-established RS cases, (17 lesions) compared with 6 early infiltrating small TC with sclerotic stroma and pseudo-RS fields. One case displayed both RS and TC foci in contiguity. Mean nuclear area was larger in the group of tubular carcinomas (51.0 μ 2 ) than in the cases o f radial sclerosis (38.30 μ 2 ). We also found a larger number of aneuploid cases in tubular carcinomas measured by image cytometry, but both types o f lesions were diploid when measured by flow cytometry; only one case of radial scar resulted aneuploid.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1995-07-01 | Pathology - Research and Practice |