6533b821fe1ef96bd127b82a
RESEARCH PRODUCT
Blood Anticoagulant Activity of Sulphated Ovular Mucins of Amphibians
A. MingantiG. Belliasubject
Multidisciplinarybiologymedicine.diagnostic_testSulfatesurogenital systemChemistryProteolysisMucinMucinsAnticoagulantsFibrinogenbiology.organism_classificationAnticoagulant activityAmphibiansPapainchemistry.chemical_compoundBiochemistrymedicineAnimalsHumanssense organsBufohormones hormone substitutes and hormone antagonistsmedicine.drugWhole blooddescription
THE mucin constituting the gelatinous layer which envelops the eggs of Bufo bufo, if digested with papain and then sulphated, shows a marked anticoagulant activity on the fibrinogen and the whole blood plasma1. A similar anticoagulant activity has now been shown by the ovular mucins of other species of amphibians, sulphated without any previous proteolysis.
year | journal | country | edition | language |
---|---|---|---|---|
1957-06-29 | Nature |