6533b821fe1ef96bd127b9e5

RESEARCH PRODUCT

Binge-like alcohol exposure in adolescence: behavioural, neuroendocrine and molecular evidence of abnormal neuroplasticity … and return

Cesare D’amicoMartin KucharGiuseppe TringaliVincenzo MicaleSalvatore FeoGianluca LavancoGianluca LavancoGianluca LavancoValentina CastelliAnna BrancatoGiuseppe PizzolantiCarla Cannizzaro

subject

Binge alcohol drinkingmedicine.medical_specialtySettore BIO/14 - FARMACOLOGIAQH301-705.5Medicine (miscellaneous)Nucleus accumbensArticleGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciences0302 clinical medicineDopamineDopamine receptor D2Internal medicineNeuroplasticityMedicineCannabidiol[SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]Biology (General)030304 developmental biologyDopamine transporter0303 health sciencesbiologyTyrosine hydroxylasebusiness.industryDopaminergicAdolescenceEndocrinologybiology.proteinNucleus accumbens[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]Adolescence Binge alcohol drinking Cannabidiol Nucleus accumbensbusinessCannabidiol030217 neurology & neurosurgerymedicine.drug

description

Binge alcohol consumption among adolescents affects the developing neural networks underpinning reward and stress processing in the nucleus accumbens (NAc). This study explores in rats the long-lasting effects of early intermittent exposure to intoxicating alcohol levels at adolescence, on: (1) the response to natural positive stimuli and inescapable stress

10.3390/biomedicines9091161http://hdl.handle.net/20.500.11769/513004