6533b821fe1ef96bd127c330

RESEARCH PRODUCT

Anti-inflammatory compounds from Sideritis javalambrensis n-hexane extract.

J. SanzS. ValverdeMaría José AlcarazR. M. RabanalAngel VillarM. J. Jimenez

subject

MaleMagnetic Resonance Spectroscopymedicine.drug_classPharmaceutical ScienceFractionationPharmacognosyAnti-inflammatoryAnalytical Chemistrychemistry.chemical_compoundMiceDrug DiscoverymedicineAnimalsHexanesPharmacologyChromatographybiologyChemistryTerpenesOrganic ChemistryAnti-Inflammatory Agents Non-SteroidalEstersPhenylethyl AlcoholPlantsbiology.organism_classificationCarrageenanTyrosolHexaneComplementary and alternative medicineBiochemistrySideritisMolecular MedicineDiterpene

description

The anti-inflammatory activities of the n-hexane extract of Sideritis javalambrensis and several purified fractions were investigated using the carrageenan mouse paw edema test. Progressive fractionation led to the isolation of the active principles ent-16-hydroxy-13-epimanoyl oxide [1] and esters of tyrosol with palmitic, stearic, behenic, and lignoceric acids.

yearjournalcountryeditionlanguage
1989-09-01Journal of natural products
10.1021/np50065a027https://pubmed.ncbi.nlm.nih.gov/2481715