6533b822fe1ef96bd127cf4e

RESEARCH PRODUCT

Effectiveness of Leukocyte and Platelet-Rich Fibrin versus Nitrofurazone on Nail Post-Surgery Bleeding and Wound Cicatrization Period Reductions: A Randomized Single Blinded Clinical Trial

Patricia Palomo-lópezRicardo Becerro-de-bengoa-vallejoXavier Garrido-castellsDaniel López-lópezCésar Calvo-loboMarta Elena Losa-iglesiasEmmanuel Navarro-flores

subject

medicine.medical_specialtyFerides i lesions TractamentAnalgesicPainnail diseaseslcsh:MedicinePostoperatoriArticleFibrinsurgery030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicinemedicineNail diseasespain030212 general & internal medicineplatelet rich plasmaInflammationNitrofurazonebiologybusiness.industrylcsh:RFoot and ankle surgeryGeneral Medicinemedicine.diseasePlatelet-rich fibrinSurgeryClinical trialExtremitatsmedicine.anatomical_structurePodologíaNail diseaseinflammationbiology.proteinNail (anatomy)EnfermeríaSurgeryPlatelet rich plasmabusiness

description

Background: Leukocyte and platelet-rich fibrin (L-PRF) may be considered a co-adjuvant intervention that may play a key role in blood coagulation and tissue repair after nail surgeries. The aim of this study was to determine the effectiveness of L-PRF versus nitrofurazone on the post-surgical bleeding and wound cicatrization period in patients with bilateral onychocryptosis during surgeries of chemical matrixectomies with 88% phenol solution. Methods: A randomized single-blind clinical trial was registered with the European Clinical Trials Database (EudraCT) with identification number 2016-002048-18. Twenty healthy participants with bilateral onychocryptosis (n = 40) were recruited and bilaterally received both protocols for both halluces. Patients with a mean age mean of 45.55 &plusmn

yearjournalcountryeditionlanguage
2019-09-27Journal of Clinical Medicine
10.3390/jcm8101552https://www.mdpi.com/2077-0383/8/10/1552