6533b822fe1ef96bd127d93b

RESEARCH PRODUCT

Delayed-type skin reactions in bursectomized or thymectomized chickens.

Alfredo SalernoA. BellaviaCalogero CarusoLivia Bellina

subject

PharmacologyMaleChemistrymedicine.medical_treatmentOxazoloneCell BiologyThymus GlandDermatitis ContactWattle (anatomy)BursectomyOxazoloneDrug HypersensitivityCellular and Molecular NeuroscienceSkin reactionchemistry.chemical_compoundBursa of FabriciusDelayed hypersensitivityImmunologymedicineMolecular MedicineAnimalsHypersensitivity DelayedMolecular BiologyNeonatal thymectomyChickens

description

Chickens can easily be induced to develop delayed-type skin reactions to oxazolone when animals are sensitized 7 days before the challenge. The reaction is quantitated by assessing the increase in wattle thickness: maximum reactions occur 24 h after challenge. The reaction is inhibited by neonatal thymectomy or bursectomy; these findings therefore suggest also an important B-derived component in delayed hypersensitivity to oxazolone.

yearjournalcountryeditionlanguage
1977-08-01Experientia
10.1007/bf01945997https://pubmed.ncbi.nlm.nih.gov/891829