6533b823fe1ef96bd127df8c

RESEARCH PRODUCT

Der Metastasendurchmesser ist entscheidend für das lokale Behandlungsergebnis nach Kryotherapie colorectaler Lebermetastasen

David L. MorrisTh. JungingerJ. K. Seifert

subject

medicine.medical_specialtyHepatic cryotherapybusiness.industryIncidence (epidemiology)Retrospective analysisMedicineRadiologybusinessTumor recurrence

description

In a retrospective analysis we aimed to assess the incidence of local recurrence at the cryosite as well as possible prognostic indicators for the disease-free interval at the cryosite following hepatic cryotherapy for non-resectable colorectal metastases. At a median follow-up of 22 months, 66 of 85 patients had developed tumor recurrence, involving local recurrence at the cryosite in 28 patients, with cryoablated metastases of >3 cm being associated with shorter disease-free intervals at the cryosite. Improvements in probe placement and monitoring of the freezing process are required to allow successful treatment of large liver metastases.

https://doi.org/10.1007/978-3-642-45774-6_355