�ber die subcellul�re Verteilung von 3,3?-Dimethyl-4,4?-diacetyldiphenylbisguanylhydrazon im Meerschweinchenherzen

6533b824fe1ef96bd127feef

RESEARCH PRODUCT

�ber die subcellul�re Verteilung von 3,3?-Dimethyl-4,4?-diacetyldiphenylbisguanylhydrazon im Meerschweinchenherzen

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Meerschweinchenherzen wurden 0,5—30 min isoliert mit 3,3′-Dimethyl-4,4′-diacetyldiphenylbisguanylhydrazon (BG 60) perfundiert, anschliesend homogenisiert und durch Differentialzentrifugation in Kern-Membran-Mitochondrien-, Mikrosomen- und Uberstands-Fraktion getrennt. Im Homogenat und in den einzelnen Fraktionen wurde die BG 60-Konzentration und der Proteingehalt bestimmt. Auserdem wurden Herzen von Tieren unmittelbar nach Infusion der Substanz oder 7 Tage danach in gleicher Weise aufgearbeitet.

year	journal	country	edition	language
1969-01-01	Naunyn-Schmiedebergs Archiv f�r Pharmakologie und Experimentelle Pathologie

https://doi.org/10.1007/bf00538775

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