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RESEARCH PRODUCT

Presentation and Outcomes of Pregnancy in Patients With Autoimmune Hepatitis

Maria García ElizMarina BerenguerMaría-carlota LondoñoMontserrat García-retortilloManuel Romero‐gomezAlbert ParésDiana HortaYolanda Sánchez TorrijosEmilio FábregaC. FernándezFederico Sáez-royuelaElena Gómez DomínguezLaura-patricia Llovet

subject

AdultPediatricsmedicine.medical_specialtyAutoimmune hepatitisCohort Studies03 medical and health sciences0302 clinical medicinePregnancyimmune system diseasesAzathioprinemedicineHumansIn patientAspartate AminotransferasesGlucocorticoidsreproductive and urinary physiologyRetrospective StudiesPregnancyHepatologybusiness.industryPostpartum PeriodPregnancy OutcomeGastroenterologyAlanine TransaminaseHypertension Pregnancy-InducedSymptom Flare Upmedicine.diseasedigestive system diseasesAbortion SpontaneousPregnancy ComplicationsDiabetes GestationalHepatitis Autoimmune030220 oncology & carcinogenesisChildbearing agePrednisoneDrug Therapy CombinationFemale030211 gastroenterology & hepatologyPresentation (obstetrics)businessImmunosuppressive AgentsPostpartum period

description

Autoimmune hepatitis (AIH) frequently affects women of childbearing age in whom the desire to have a family raises the question regarding the potential risks for the fetus and the mother. The information on AIH in pregnant patients is scarce.1 The aims of this study were (1) to identify the risk factors associated with flares in pregnant patients diagnosed with AIH, (2) to determine the course of AIH in patients with pregnancy-related flares, and (3) to describe the outcome of AIH diagnosed in the postpartum period.

https://doi.org/10.1016/j.cgh.2018.12.030