6533b824fe1ef96bd12801ac

RESEARCH PRODUCT

Glaucoma and Antioxidants: Review and Update

Alejandro Cobo-martinezMaria Dolores Lopez-bernalVicente Zanon-morenoVicente Zanon-morenoMonica Del-rio-vellosilloElena Rubio-velazquezJose Javier Garcia-medinaMaria D Pinazo-duranMaria D Pinazo-duran

subject

antioxidantgenetic structuresPhysiologyClinical BiochemistryGlaucomaDiseaseReviewmedicine.disease_causeBioinformaticsBiochemistryRetinal ganglion03 medical and health sciences0302 clinical medicinemedicineoxidative stressMolecular Biologybusiness.industrylcsh:RM1-950Cell Biologymedicine.diseaseeye diseasesClinical trialglaucomalcsh:Therapeutics. Pharmacology030221 ophthalmology & optometrysense organsbusiness030217 neurology & neurosurgeryOxidative stress

description

Glaucoma is a neurodegenerative disease characterised by the progressive degeneration of retinal ganglion cells. Oxidative stress has been related to the cell death in this disease. Theoretically, this deleterious consequence can be reduced by antioxidants substances. The aim of this review is to assemble the studies published in relation to antioxidant supplementation and its effects on glaucoma and to offer the reader an update on this field. With this purpose, we have included studies in animal models of glaucoma and clinical trials. Although there are variable results, supplementation with antioxidants in glaucoma may be a promising therapy in glaucoma.

10.3390/antiox9111031https://www.mdpi.com/2076-3921/9/11/1031