0000000000544131

AUTHOR

Maria Dolores Lopez-bernal

showing 2 related works from this author

Glaucoma and Antioxidants: Review and Update

2020

Glaucoma is a neurodegenerative disease characterised by the progressive degeneration of retinal ganglion cells. Oxidative stress has been related to the cell death in this disease. Theoretically, this deleterious consequence can be reduced by antioxidants substances. The aim of this review is to assemble the studies published in relation to antioxidant supplementation and its effects on glaucoma and to offer the reader an update on this field. With this purpose, we have included studies in animal models of glaucoma and clinical trials. Although there are variable results, supplementation with antioxidants in glaucoma may be a promising therapy in glaucoma.

antioxidantgenetic structuresPhysiologyClinical BiochemistryGlaucomaDiseaseReviewmedicine.disease_causeBioinformaticsBiochemistryRetinal ganglion03 medical and health sciences0302 clinical medicinemedicineoxidative stressMolecular Biologybusiness.industrylcsh:RM1-950Cell Biologymedicine.diseaseeye diseasesClinical trialglaucomalcsh:Therapeutics. Pharmacology030221 ophthalmology & optometrysense organsbusiness030217 neurology & neurosurgeryOxidative stressAntioxidants
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Optical Coherence Tomography Angiography of Macula and Optic Nerve in Autism Spectrum Disorder: A Pilot Study

2020

The aim of this study was to compare retinal thicknesses and vascular parameters between autism spectrum disorder (ASD) and neurotypical (NT) individuals. Recruited ASD subjects and age- and sex-matched NT controls underwent 2 optical coherence tomography scans (OCT) (macular cube and optic nerve cube) and 2 OCT angiography (OCTA) scans (macular and optic nerve head (ONH) OCTA) with the device Cirrus 5000 (Zeiss). Concerning OCT, we considered full retina thickness in 9 macular sectors of the Early Treatment Diabetic Retinopathy Study (ETDRS) pattern and peripapillary retinal nerve fiber layer (pRNFL) thickness in 4 quadrants and 12 clock-hour sectors. Vessel density and capillary perfusion…

medicine.medical_specialtygenetic structuresNerve fiber layerlcsh:Medicineautism spectrum disorderoptical coherence tomography angiographyArticleoptic nerveperfusion03 medical and health scienceschemistry.chemical_compound0302 clinical medicineOptical coherence tomographyOphthalmologyvessel densitymedicinemacula030304 developmental biology0303 health sciencesRetinamedicine.diagnostic_testbusiness.industrylcsh:RautoregulationRetinalneurotypicalGeneral MedicineDiabetic retinopathymedicine.diseaseeye diseasesthicknessfluxmedicine.anatomical_structurechemistryAutism spectrum disorderOptic nervesense organsbusinessPerfusion030217 neurology & neurosurgeryJournal of Clinical Medicine
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