6533b824fe1ef96bd1281341

RESEARCH PRODUCT

Comment on "Human Neuroblasts Migrate to the Olfactory Bulb via a Lateral Ventricular Extension"

Mitchel S. BergerMitchel S. BergerArturo Alvarez-buyllaArturo Alvarez-buyllaJosé Manuel García-verdugoJosé Manuel García-verdugoNader SanaiNader Sanai

subject

MultidisciplinaryNeuroblastCell growthbiology.proteinAnatomyCell movementBiologyCell shapeOlfactory bulbCell biologyProliferating cell nuclear antigen

description

Curtis et al . (Research Articles, 2 March 2007, p. 1243) claimed discovery of a human neuronal migratory stream to the olfactory bulb along a putative lateral ventricular extension. However, high levels of proliferation reported with proliferating cell nuclear antigen were not confirmed using different markers, neuronal chain migration was not demonstrated, and no serial reconstruction shows a true ventricular extension.

yearjournalcountryeditionlanguage
2007-10-19Science
https://doi.org/10.1126/science.1145011