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RESEARCH PRODUCT

Cannabis Influences the Putative Cytokines-Related Pathway of Epilepsy among Egyptian Epileptic Patients

Mohammed Talat AbbasM. S. DarwishYasmeen M. TaalabYasmeen M. TaalabWessam Fathi MohammedIbrahim HassanAlyaa A. A. OthmanManar A Helmy

subject

cannabismedicine.medical_specialtypurified cannabidiol (cbd)inflammatory cytokinesmedicine.medical_treatmenttreatment-resistant epilepsyArticlelcsh:RC321-571Proinflammatory cytokine03 medical and health sciencesEpilepsy0302 clinical medicineInternal medicinemedicineanticonvulsant drugslcsh:Neurosciences. Biological psychiatry. Neuropsychiatryseizures030304 developmental biology0303 health sciencesbiologybusiness.industryGeneral NeuroscienceInterleukintetrahydrocannabinol (thc)Cannabis useUniversity hospitalbiology.organism_classificationmedicine.diseaseCytokineepilepsyTumor necrosis factor alphaCannabisbusiness030217 neurology & neurosurgery

description

The study aims to investigate: (1) the prevalence of cannabis among epileptic patients seen at Mansoura University Hospital, (2) serum levels and gene expression of cytokines in epilepsy patients and the controls. and (3) the possibility that cannabis use affects the cytokine levels in epilepsy patients, triggering its future use in treatment. We recruited 440 epilepsy patients and 200 controls matched for age, gender, and ethnicity. Of the epileptic patients, 37.5% demonstrated lifetime cannabis use with a mean duration of 15 &plusmn

yearjournalcountryeditionlanguage
2019-11-20Brain Sciences
https://doi.org/10.3390/brainsci9120332