6533b825fe1ef96bd1281baa

RESEARCH PRODUCT

From over-stoichiometric to sub-stoichiometric enantioselective protonation with 2-sulfinyl alcohols: A view in perspective

M. Medio-simónP. AlemánAna Belen CuencaJ. GilN. RodríguezG. Asensio

subject

Enantioselective protonationUNESCO::QUÍMICA:QUÍMICA::Química orgánica [UNESCO]Sulfinyl alcoholsEnolatesEnolates ; Enantioselective protonation ; Sulfinyl alcoholsUNESCO::QUÍMICA::Química orgánica:QUÍMICA [UNESCO]

description

A general study of the enantioselective protonation of prochiral enolates with 2-sulfinyl alcohols is reported. The modification of reaction conditions to reduce drastically the amount of chiral proton source needed to obtain a good enantiomeric excess is reported. The effects of the different factors controlling the stereoselectivity are clearly established. Different protocols for enolate generation are compared. Medio Simon, Mercedes, Mercedes.Medio@uv.es ; Aleman Lopez, Pedro Antonio, Pedro.Aleman@uv.es ; Gil Tomas, Jesus Javier, Jesus.J.Gil@uv.es ; Asensio, Aguilar Gregorio, Gregorio.Asensio@uv.es

yearjournalcountryeditionlanguage
2005-01-01
http://www.scopus.com/inward/record.url?eid=2-s2.0-20044386201&partnerID=MN8TOARS