6533b825fe1ef96bd128291a

RESEARCH PRODUCT

Core/Shell Gel Beads with Embedded Halloysite Nanotubes for Controlled Drug Release

Stefana MiliotoGiuseppe CavallaroGiuseppe LazzaraLorenzo LisuzzoRawil FakhrullinFilippo Parisi

subject

ChitosanNanotubeMaterials scienceNanocompositeAlginateNanoparticleHalloysiteDrug releaseSurfaces and Interfacesengineering.materialHalloysiteSurfaces Coatings and FilmsChitosangel beadschemistry.chemical_compoundChemical engineeringchemistryCoatinglcsh:TA1-2040Gel beadMaterials ChemistryengineeringMoleculelcsh:Engineering (General). Civil engineering (General)Layer (electronics)

description

The use of nanocomposites based on biopolymers and nanoparticles for controlled drug release is an attractive notion. We used halloysite nanotubes that were promising candidates for the loading and release of active molecules due to their hollow cavity. Gel beads based on chitosan with uniformly dispersed halloysite nanotubes were obtained by a dropping method. Alginate was used to generate a coating layer over the hybrid gel beads. This proposed procedure succeeded in controlling the morphology at the mesoscale and it had a relevant effect on the release profile of the model drug from the nanotube cavity.

yearjournalcountryeditionlanguage
2019-01-24Coatings
https://doi.org/10.3390/coatings9020070