6533b825fe1ef96bd1282a84

RESEARCH PRODUCT

A New Aromatic Compound from the Stem Bark of Terminalia catappa

Patrick DutartreTomofumi MiyamotoDavid PertuitStéphanie DelemasureChiaki TanakaAnne Claire Mitaine-offerMarie Aleth Lacaille-dubois

subject

PharmacologyStem barkMagnetic Resonance SpectroscopyCombretaceaeMolecular StructurePlant StemsbiologyPlant ExtractsChemistryArjunolic acidTerminaliaPlant ScienceGeneral Medicinebiology.organism_classificationTerpeneAntioxidant capacityComplementary and alternative medicineDrug DiscoveryPlant BarkTerminaliaOrganic chemistryCytotoxicityTwo-dimensional nuclear magnetic resonance spectroscopy

description

A new aromatic compound 3,4,5-trimethoxyphenyl-1- O-(4-sulfo)-β-D-glucopyranoside (1), in addition to two triterpenoid saponins (chebuloside II, arjunoglucoside II), two triterpenes (arjunolic acid and 3-betulinic acid) and sitosterol-3- O-β-D-glucopyranoside have been isolated from the barks of Terminalia catappa. Their structures have been established on the basis of spectroscopic techniques (1D/2D NMR) and MS. Their cytotoxicity and anti-inflammatory activity, together with the antioxidant capacity of compound 1 were also evaluated.

https://doi.org/10.1177/1934578x1501000652