Non-infectious uveitis burden on quality of life and work impairment assessed through different psychometric questionnaires

6533b825fe1ef96bd128332c

RESEARCH PRODUCT

Non-infectious uveitis burden on quality of life and work impairment assessed through different psychometric questionnaires

Michele Figus Lorenzo Vannozzi Paolo Mora Giuliana Gualberti Paola Balestrieri Francesca Marando Francesca Romana Florio Luca Cimino Maria Vadalà Piergiorgio Neri Piergiorgio Neri Maria Pia Paroli Leonardo Mastropasqua Massimo Accorinti Barbara Iaccheri Maurizio Fossarello Elisabetta Miserocchi Caterina Gagliano

subject

Male medicine.medical_specialty QoL Psychometrics Referral Visual Acuity uveitis questionnaire; QoL; disease burden; work impairment Disease Affect (psychology)Uveitis disease burden Infectious uveitis Quality of life Cronbach's alpha work impairment Surveys and Questionnaires medicine Humans Disease burden business.industry Reproducibility of Results General Medicine medicine.disease Ophthalmology QoL; Uveitis questionnaire; disease burden; work impairment Quality of Life Physical therapy disease burden QoL Uveitis questionnaire work impairment Female business Uveitis questionnaire Uveitis uveitis questionnaire

description

Background: The purpose of this study was to evaluate the association between a novel psychometric 12-item questionnaire (U-qest) and other validated questionnaires to assess quality of life and work impairment in patients with non-infectious uveitis. Methods: Data were collected at baseline and 3 months postbaseline using U-qest and two other validated questionnaires: The National Eye Institute 25-Item Visual Function Questionnaire (VFQ-25) and the 12-Item Short-Form Health Survey (SF-12). Results: A total of 136 patients (52.2% female) aged 47.9 ± 14.8 years (mean ± SD) were enrolled in 14 uveitis referral centres. U-qest correlated moderately with VFQ-25 and SF-12 at baseline and at 3 months. Both U-qest and VFQ-25 scores improved as disease improved; however, U-qest also detected improvement in patients for whom VFQ-25 scores did not improve. Disease activity was shown to significantly affect activity impairment. Patients and physicians expressed positive perceptions regarding the use and benefit of this instrument. U-qest showed very good reliability in terms of internal consistency (Cronbach’s alpha = 0.91). Conclusions: U-qest can be considered a useful tool to assess the burden of uveitis on quality of life.

year	journal	country	edition	language
2021-08-16

10.1177/11206721211034649 http://hdl.handle.net/11568/1105138