6533b826fe1ef96bd1283adc

RESEARCH PRODUCT

Massenspektrometrische Untersuchungen an 4(5)-Hydroxymethyl-imidazolen

Hannelore SitziusWalter SchunackHans-joachim Sattler

subject

chemistry.chemical_compoundchemistryFragmentation (mass spectrometry)Drug DiscoveryPharmaceutical ScienceHydroxymethylMass spectrometryMedicinal chemistry

description

Es wurden 12 unterschiedlich substituierte Hydroxymethylimidazole massenspektrometrisch untersucht und die charakteristischen Schlusselbruchstucke beschrieben. Fur den Zerfall von 4(5)-Hydroxymethyl-imidazol (1) und 5-Hydroxymethyl-1-methyl-imidazol (8) werden Fragmentierungsschemata angegeben. Mass Spectrometry of 4(5)-Hydroxymethylimidazoles 12 substituted hydroxymethylimidazoles were investigated by mass spectrometry. The characteristic fragments are described. Schemes for the fragmentation of 4(5)-hydroxymethylimidazole (1) and 5-hydroxymethyl-1-methylimidazole (8) are reported.

https://doi.org/10.1002/ardp.19793121204