Investigating the Vascular Toxicity Outcomes of the Irreversible Proteasome Inhibitor Carfilzomib

6533b826fe1ef96bd1283e5d

RESEARCH PRODUCT

Investigating the Vascular Toxicity Outcomes of the Irreversible Proteasome Inhibitor Carfilzomib

Svenja Siemer Claudius Witzler Evangelos Terpos Ioanna Andreadou Panagiota-efstathia Nikolaou Philip Wenzel Efstathios Kastritis Hendrik Doerschmann Roland H. Stauber Meletios A. Dimopoulos Panagiotis Efentakis Panagiotis Efentakis

subject

Male 0301 basic medicine vasculature 030204 cardiovascular system & hematology Pharmacology Dinoprost Endoplasmic Reticulum lcsh:Chemistry Mice chemistry.chemical_compound 0302 clinical medicine AMP-Activated Protein Kinase Kinases vascular smooth muscle cells Cytotoxicity lcsh:QH301-705.5 endoplasmatic-reticulum stress Spectroscopy chemistry.chemical_classification carfilzomib Cobalt General Medicine Metformin Computer Science Applications Respiratory burst Metformin Drug Therapy Combination Glycolysis Oligopeptides Proteasome Inhibitors medicine.drug Proteasome Endopeptidase Complex autophagy Cell Survival Myocytes Smooth Muscle Antineoplastic Agents Nitric Oxide Article Catalysis Inorganic Chemistry 03 medical and health sciences medicine Animals Humans Physical and Theoretical Chemistry Molecular Biology Reactive oxygen species business.industry Organic Chemistry Autophagy Carfilzomib Actins Vasoprotective Mice Inbred C57BL Glucose 030104 developmental biology chemistry lcsh:Biology (General)lcsh:QD1-999 Proteasome inhibitor Tumor Suppressor Protein p53 Reactive Oxygen Species business Protein Kinases

description

Background: Carfilzomib&rsquo

year	journal	country	edition	language
2020-07-22	International Journal of Molecular Sciences

10.3390/ijms21155185 http://dx.doi.org/10.3390/ijms21155185

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