6533b826fe1ef96bd128465a
RESEARCH PRODUCT
Bioactive saponins from plants: An update
Marie-aleth Lacaille-duboisH. Wagnersubject
Antifungalchemistry.chemical_classificationBroad spectrumchemistryTriterpenemedicine.drug_classmedicine.medical_treatmentmedicineGlycosidePharmacologyBiologyImmunoadjuvantSteroiddescription
Plant saponins are a group of naturally occuring triterpene or steroid glycosides which include a large number of biologically and pharmacologically active compounds. Saponins have been shown in both in vitroand in vivoexperimental test systems during the last decade to possess a broad spectrum of biological and pharmacological activities. This review will summarize some of the recent advances concerning cancer-related activity, immunostimulating, immunoadjuvant, antihepatotoxic, antiphlogistic, antiallergic, molluscicidal, hemolytic, antifungal, antiviral, and hypoglycemic activities. In addition, the effects on the cardiovascular system and the central nervous system will be discussed together with other miscellaneous effects. Studies of structure/activity relationships and mechanism of action will be presented.
year | journal | country | edition | language |
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2000-01-01 |