6533b826fe1ef96bd128492e

RESEARCH PRODUCT

1 Hz repetitive transcranial magnetic stimulation of the unaffected hemisphere ameliorates contralesional visuospatial neglect in humans

Edoardo BisiachOrnella DanieleAurelio PiazzaV. La BuaFilippo BrighinaMassimiliano OliveriBrigida Fierro

subject

Malemedicine.medical_specialtyVisual perceptionmedia_common.quotation_subjectmedicine.medical_treatmentPosterior parietal cortexVisuospatial neglectNeurological disorderAudiologybehavioral disciplines and activitiesLateralization of brain functionBrain IschemiaNeglectPerceptual DisordersElectromagnetic FieldsParietal LobemedicineHumansAgedmedia_commonGeneral NeuroscienceMiddle AgedEvoked Potentials Motormedicine.diseaseTranscranial magnetic stimulationTreatment OutcomeSpace PerceptionCerebral hemisphereAgnosiaVisual PerceptionPsychologyNeurosciencePsychomotor Performancepsychological phenomena and processes

description

The aim of the study was to investigate whether low-frequency repetitive transcranial magnetic stimulation (rTMS) over the unaffected hemisphere can ameliorate visuospatial neglect. We treated three right brain damaged patients with left neglect. 900 pulses (1 Hz frequency) were given over left posterior parietal cortex every other day for 2 weeks. Patients performed a computerized task requiring length judgement of prebisected lines, tachistoscopically presented for 150 ms. With respect to rTMS the task was given 15 days before, at the beginning, at the end and 15 days after. At these times patients performed also line bisection and clock drawing tasks. rTMS induced a significant improvement of visuo-spatial performance that remained quite unchanged 15 days after. Patients performance at Time 3 and 4 improved also as concerns line bisection and clock drawing tasks.

https://doi.org/10.1016/s0304-3940(02)01283-1