6533b826fe1ef96bd1284efb
RESEARCH PRODUCT
Effects of Some Directly-Acting Smooth Muscle Relaxant Drugs on Isolated Human Preparations of the Upper Urinary Tract
H. NawrathL. Hertlesubject
DrugPapaverinebusiness.industrymedia_common.quotation_subjectPharmacologyAutonomic nervous systemSmooth musclemedicineUrological DisordersAntispasmodicbusinessAnticholinergic Drugsmedicine.drugmedia_commonUpper urinary tractdescription
It is generally assumed that drugs which induce relaxation of smooth muscles may be of clinical importance in some urological disorders; such drugs are indeed widely used, for example in the therapy of unstable bladders or to facilitate the passage of ureteral stones. Antispasmodic action may be classified in neurotropic and musculo-tropic action; the former acting on the autonomic nervous system and the latter directly on smooth muscle cells. Examples for the first type of action are anticholinergic drugs or alpha-adrenoceptor-antagonists, whereas papaverine is a classic drug with the second type of action.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1985-01-01 |