6533b827fe1ef96bd128654b

RESEARCH PRODUCT

Unusual epithelial-myoepithelial carcinoma in palate: case report and immunohistochemical study

Luiz Augusto Costa Da SilvaDaliana Queiroga De Castro GomesLélia Maria Guedes QueirozPollianna Muniz AlvesHébel Galvão CavalcantiGustavo Pina Godoy

subject

Pathologymedicine.medical_specialtymedicine.diagnostic_testAdenoid cystic carcinomabusiness.industryMyoepithelial cellOdontología:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseEpithelial-myoepithelial carcinomaCiencias de la saludParotid glandmedicine.anatomical_structureMajor Salivary GlandBiopsyUNESCO::CIENCIAS MÉDICASmedicineCarcinomaAdenocarcinomabusinessGeneral Dentistry

description

Ephitelial-myoepithelial carcinoma (EMC) is a neoplasm of salivary gland extremely rare and low-grade malig- nant, exhibiting predilection for major salivary gland, especially parotid gland. This paper described a case of EMC localized in soft palate. The initial clinical diagnosis were mucoepidermoid and adenoid cystic carcinoma. A incisional biopsy was performed, and the histological diagnosis was adenocarcinoma not otherwise specified. The patient underwent excisional biopsy, where was realized immunohistochemical analysis, staining the duct-like structures, where the inner layer of epithelial cells positively for CK 14, whereas outer layer of myoepithelial cells stained positively for smooth muscle actin (SMA) and vimentin antibodies. Based on these findings, the final histological diagnosis was EMC. The patient was submitted 30 sessions of radiotherapy, and she is being follow-up about 2 years without evidence recurrences.

yearjournalcountryeditionlanguage
2010-01-01
http://hdl.handle.net/10550/54532