6533b827fe1ef96bd1286733
RESEARCH PRODUCT
Short term association between ozone and mortality: global two stage time series study in 406 locations in 20 countries
Cong LiuAi MilojevicJoana MadureiraJoana MadureiraJan KyselýJan KyselýEvangelia SamoliMagali Hurtado-díazMartin RöösliMartin RöösliHans OrruHaidong KanCarmen IñiguezChristofer ÅStrömNoah ScovronickHo KimMartina S. RagettliMartina S. RagettliYueliang Leon GuoJulio CruzFrancesco SeraEne IndermitteRebecca M. GarlandRebecca M. GarlandRebecca M. GarlandAurelio TobiasMathilde PascalMatteo ScortichiniBing-yu ChenChris Fook Sheng NgYasushi HondaBertil ForsbergKlea KatsouyanniKlea KatsouyanniMassimo StafoggiaMasahiro HashizumeAntonella ZanobettiEric LavigneEric LavigneAleš UrbanYuming GuoBen ArmstrongVeronika HuberVeronika HuberSusana SilvaShilu TongShilu TongShilu TongAlexandra SchneiderMichelle L. BellJoel SchwartzAna M. Vicedo-cabreraAna M. Vicedo-cabreraAna M. Vicedo-cabreraAntonio Gasparrinisubject
OzoneClimate ChangeInternational CooperationShort term mortality610 Medicine & health010501 environmental sciencesGlobal Health01 natural sciences03 medical and health scienceschemistry.chemical_compoundArbetsmedicin och miljömedicin0302 clinical medicineOzone360 Social problems & social servicesEnvironmental healthAir PollutionHumans030212 general & internal medicineTime series studyCitiesMortality610 Medicine & health0105 earth and related environmental sciencesExcess mortalitySeries (stratigraphy)Ar e Saúde OcupacionalResearchGeneral MedicineOccupational Health and Environmental HealthEnvironmental ExposureTerm (time)Environmental PolicyGeographychemistryMulticenter studyAir qualityStage (hydrology)SeasonsDeterminantes da Saúde e da Doença360 Social problems & social servicesdescription
Objective To assess short term mortality risks and excess mortality associated with exposure to ozone in several cities worldwide. Design Two stage time series analysis. Setting 406 cities in 20 countries, with overlapping periods between 1985 and 2015, collected from the database of Multi-City Multi-Country Collaborative Research Network. Population Deaths for all causes or for external causes only registered in each city within the study period. Main outcome measures Daily total mortality (all or non-external causes only). Results A total of 45 165 171 deaths were analysed in the 406 cities. On average, a 10 µg/m3 increase in ozone during the current and previous day was associated with an overall relative risk of mortality of 1.0018 (95% confidence interval 1.0012 to 1.0024). Some heterogeneity was found across countries, with estimates ranging from greater than 1.0020 in the United Kingdom, South Africa, Estonia, and Canada to less than 1.0008 in Mexico and Spain. Short term excess mortality in association with exposure to ozone higher than maximum background levels (70 µg/m3) was 0.26% (95% confidence interval 0.24% to 0.28%), corresponding to 8203 annual excess deaths (95% confidence interval 3525 to 12 840) across the 406 cities studied. The excess remained at 0.20% (0.18% to 0.22%) when restricting to days above the WHO guideline (100 µg/m3), corresponding to 6262 annual excess deaths (1413 to 11 065). Above more lenient thresholds for air quality standards in Europe, America, and China, excess mortality was 0.14%, 0.09%, and 0.05%, respectively. Conclusions Results suggest that ozone related mortality could be potentially reduced under stricter air quality standards. These findings have relevance for the implementation of efficient clean air interventions and mitigation strategies designed within national and international climate policies.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-02-10 |