6533b828fe1ef96bd128795b
RESEARCH PRODUCT
Autoimmune ear disease: clinical and diagnostic relevance in Cogan’s sydrome
Luigi MaiolinoAgostino SerraSalvatore CocuzzaAngelo ContiSalvatore GallinaLuisa Licciardellosubject
Autoimmune ear disordermedicine.medical_specialtyPathologyInterstitial keratitisHearing lossEar diseaseCase ReportDisease03 medical and health sciences0302 clinical medicinemedicineotorhinolaryngologic diseases030223 otorhinolaryngologyAortitis030203 arthritis & rheumatologyCogan’s syndromebusiness.industryAutoimmune inner ear diseaseHearing lossmedicine.diseaselcsh:OtorhinolaryngologyDermatologylcsh:RF1-547OtorhinolaryngologyHearing loss.Sensorineural hearing lossAutoimmune ear disorder; Cogan’s syndrome; Hearing loss.medicine.symptombusinessSystemic vasculitisdescription
The autoimmune inner ear disease is a clinical syndrome with uncertain pathogenesis that is often associated to rapidly progressive hearing loss that, especially at the early stages of disease, may be at monoaural localization, although more often it is at binaural localization. It usually occurs as a sudden deafness, or a rapidly progressive sensorineural hearing loss. In this study a particular form of autoimmune inner ear disease is described, Cogan’s syndrome. Cogan’s syndrome is a chronic inflammatory disorder that most commonly affects young adults. Clinical hallmarks are interstitial keratitis, vestibular and auditory dysfunction. Associations between Cogan’s syndrome and systemic vasculitis, as well as aortitis, also exist. We report a case of a young woman who presented audiological and systemic characteristics attributable to Cogan’s syndrome. In the description of the case we illustrate how the appearance and evolution of the disease presented.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2017-03-01 | Audiology Research |