6533b828fe1ef96bd12879e1
RESEARCH PRODUCT
Describing the gingival involvement in a sample of 182 Italian predominantly oral mucous membrane pemphigoid patients: A retrospective series
Roberto BroccolettiMario CarboneSilvia GiacomettiPaolo-giacomo ArduinoDavide ConrottoErica PettigianiMarco CarrozzoAlessandra EliaAlessio Gambinosubject
Clinical features; Gingival status; Mucous membrane pemphigoid; Surgery; Otorhinolaryngology; 2734; Pathology and Forensic Medicine; Dentistry (all)Malemedicine.medical_specialtyMucous membrane pemphigoidGingival status2734Pemphigoid Benign Mucous MembraneDentistryOral cavityOral mucous membrane pemphigoidPathology and Forensic Medicine030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineMedicineHumansGeneral DentistryDirect fluorescent antibodyAgedRetrospective StudiesOral Medicine and Pathologybusiness.industryResearchBenign Mucous MembraneMean ageRetrospective cohort studyClinical features030206 dentistryMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseDermatologyOtorhinolaryngologyItalyMale patientUNESCO::CIENCIAS MÉDICASGingival DiseasesDentistry (all)SurgeryFemalebusinessOral medicinePemphigoidAged; Female; Gingival Diseases; Humans; Italy; Male; Middle Aged; Pemphigoid Benign Mucous Membrane; Retrospective StudiesGingival diseasedescription
Background The oral cavity has been frequently described as the only site of involvement or as the first manifestation of mucous membrane pemphigoid (MMP), being the gingival tissues often involved, but usually this has been effusively detailed in limited case series. This is a retrospective evaluation of the gingival involvement in 182 Italian patients with oral MMP. Material and Methods The diagnosis of MMP was established by both clinical morphology and direct immunofluorescence finding. Patient information (age, gender, risk factors and medical status) and parameters of manifestation (lesions’ distribution, site and type) were detailed. Results The mean age was 62 years for women (n=137) and 67 years for men (n=45). Patients had several sites of oral involvement; the gingiva was the most common one, affecting 151 patients (82.96%; 119 f - 32 m). Female subjects had more possibilities to develop gingival lesions than male patients (P = 0.005). Sixty-five patients (35.7%; 58 f - 7 m) had pure gingival involvement. Patients with lower gingival involvement statistically had more complaints (P = 0.006). Conclusions This report is one of the largest about predominantly oral MMP cases, detailing the very frequent gingival involvement; this could be crucial not only for oral medicine specialists but also for primary dental healthcare personnel and for periodontists. Key words:Mucous membrane pemphigoid, gingival status, clinical features.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2016-05-23 |