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RESEARCH PRODUCT
Energy Balance and Risk of Mortality in Spanish Older Adults
Helmut SchröderEmilio RosEmilio RosÁNgel M. Alonso-gómezÁNgel M. Alonso-gómezAlfredo GeaAlfredo GeaMontserrat FitóMiquel FiolXavier PintóLuis Serra-majemLluis Serra-majemEstefanía ToledoEstefanía ToledoRaquel CuetoRaquel CuetoÁLvaro HernáezJordi Salas-salvadóJosé V SorlíJosé V. SorlíDolores CorellaDolores CorellaOlga CastañerNancy BabioCamille LassaleJosé LapetraRamon Estruchsubject
Malemedicine.medical_specialtyEpidemiologyEnergy balance030204 cardiovascular system & hematologyLower riskDiet SurveysArticlePersones grans03 medical and health sciences0302 clinical medicineCause of DeathNeoplasmsEpidemiologyRisk of mortalityMortalitatMedicineHumansTX341-641030212 general & internal medicineProspective StudiesMortalityProspective cohort studyEpidemiologiaCardiovascular mortalityAgedProportional Hazards ModelsNutrition and Dieteticsbusiness.industryNutrition. Foods and food supplyHazard ratioenergy balancemortalityDietCardiovascular DiseasesSpainCohortepidemiologyFemaleOlder peoplebusinessEnergy IntakeEnergy MetabolismFood ScienceDemographydescription
Clinical data on the direct health effects of energy deficit or surplus beyond its impact on body weight are scarce. We aimed to assess the association with all-cause, cardiovascular and cancer mortality of (1) sustained energy deficit or surplus, calculated according to each individual’s en-ergy intake (EI) and theoretical energy expenditure (TEE), and (2) mid-term change in total EI in a prospective study. In 7119 participants in the PREDIMED Study (PREvención con DIeta MEDi-terránea) with a mean age of 67 years, energy intake was derived from a 137-item food frequency questionnaire. TEE was calculated as a function of age, sex, height, body weight and physical ac-tivity. The main exposure was the proportion of energy requirement covered by energy intake, cumulative throughout the follow-up. The secondary exposure was the change in energy intake from baseline. Cox proportional hazard models were used to estimate hazard ratios and 95% con-fidence intervals for all-cause, cardiovascular and cancer mortality. Over a median follow-up of 4.8 years, there were 239 deaths (excluding the first 2 years). An energy intake exceeding energy needs was associated with an increase in mortality risk (continuous HR10% over energy needs = 1.10
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2021-05-04 |