6533b828fe1ef96bd12882e2

RESEARCH PRODUCT

Heart in Hyperthyroidism

Bernadette BiondiGeorge J. Kahaly

subject

endocrine systemmedicine.medical_specialtyendocrine system diseasesbusiness.industryThyroidmedicine.diseasePreloadmedicine.anatomical_structureHeart failureInternal medicineVascular resistanceCardiologyMedicineEndocrine systembusinesshormones hormone substitutes and hormone antagonistsCardiovascular mortalitySubclinical infectionHormone

description

Hyperthyroidism is a common endocrine disorder that produces important clinical consequences on the cardiovascular system. In overt hyperthyroidism the increase in left ventricular performance is predominantly sustained by an increased preload with enhanced left ventricular diastolic function and reduced systemic vascular resistance. The pattern of cardiovascular abnormalities is similar in subclinical and overt hypothyroidism, suggesting that a lesser degree of thyroid hormone deficiency may also affect the cardiovascular system. Untreated overt and subclinical hypothyroidism can lead to an increased risk of coronary heart disease (CHD), heart failure (HF), and cardiovascular mortality.

yearjournalcountryeditionlanguage
2019-01-01
https://doi.org/10.1007/978-3-319-72102-6_26