Enhanced Antibacterial Activity of Repurposed Mitomycin C and Imipenem in Combination with the Lytic Phage vB_KpnM-VAC13 against Clinical Isolates of Klebsiella pneumoniae.

6533b828fe1ef96bd128848f

RESEARCH PRODUCT

Enhanced Antibacterial Activity of Repurposed Mitomycin C and Imipenem in Combination with the Lytic Phage vB_KpnM-VAC13 against Clinical Isolates of Klebsiella pneumoniae.

Olga Pacios Laura Fernández-garcía Ines Bleriot Lucía Blasco Mónica González-bardanca María López Felipe Fernández-cuenca Jesus Oteo-iglesias ÁLvaro Pascual Luis Martínez-martínez Pilar Domingo-calap Germán Bou María Tomás Spanish Society Of Infectious Diseases And Clinical Microbiology (Seimc). Study Group On Mechanisms Of Action And Resistance To Antimicrobials (Gemara)

subject

0301 basic medicine Imipenem Klebsiella pneumoniae medicine.drug_class Mitomycin 030106 microbiology Antibiotics Resistance Drug repurposing Microbial Sensitivity Tests Bacteriophage therapy beta-Lactamases Microbiology Persistence 03 medical and health sciences Mechanisms of Resistance medicine polycyclic compounds Humans Pharmacology (medical)Bacteriophages Pathogen health care economics and organizations Pharmacology biology Mitomycin C Broth microdilution biochemical phenomena metabolism and nutrition biology.organism_classification Antimicrobial humanities Anti-Bacterial Agents Klebsiella Infections Synergy Imipenem Klebsiella pneumoniae 030104 developmental biology Infectious Diseases Lytic cycle medicine.drug

description

Study Group on Mechanisms of Action and Resistance to Antimicrobials (GEMARA) on behalf of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC).

year	journal	country	edition	language
2021-08-17	Antimicrobial agents and chemotherapy

10.1128/aac.00900-21 https://pubmed.ncbi.nlm.nih.gov/34228538

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