6533b828fe1ef96bd12884d8

RESEARCH PRODUCT

Management of ulcerative colitis in a real-life setting: An Italian multicenter, prospective, observational AIGO study

Elisabetta BuscariniFrancesco CostaMaria CappelloAurora BortoliClaudio PapiNicoletta OrzesAnna KohnL. CasertaFrancesco BortoluzziFrancesco MangusoAntonio FerronatoSilvia MazzuoliMaria Lia ScribanoClaudio Camillo Cortelezzi

subject

AdultMalemedicine.medical_specialtyAdolescentDiseaseReal life settingSeverity of Illness IndexYoung Adult03 medical and health sciences0302 clinical medicineSurveys and QuestionnairesHumansMedicineProspective StudiesMedical prescriptionAgedAged 80 and overHepatologyManagement of ulcerative colitisbusiness.industryGastroenterologyDisease ManagementMiddle Agedmedicine.diseaseUlcerative colitisHospitalizationClinical PracticeCross-Sectional StudiesItaly030220 oncology & carcinogenesisPractice Guidelines as TopicPublic hospitalEmergency medicineColitis UlcerativeFemale030211 gastroenterology & hepatologyObservational studyGuideline Adherencebusiness

description

Abstract Background No data are available on the variability in the clinical management of ulcerative colitis (UC) patients by Italian gastroenterologists. Therefore, improving the standards of UC care as provided by the National Welfare Clinical Path (PDTA), in accordance with the European Crohn’s and Colitis Organization (ECCO) guidelines for UC, is not easy. Aims To assess the management of UC by Italian gastroenterologists in a real-life setting taking into account its variability. Methods This prospective, cross-sectional, observational study included IBD-specialized gastroenterologists (GSIBDs) and general gastroenterologists (GGs) working in Italian public hospital units. Consecutive patients with an UC flare were enrolled and the medical treatment evaluated. For each center, the physician in charge of the study (16 GSIBDs and 10 GGs) was administered two electronic questionnaires. Results Among 26 units, 573 UC patients were enrolled. Good adherence to the European guidelines was reported; GSIBDs reported greater adherence than GGs with a higher prescription of rectal and combination therapy in mild to moderate distal disease and a higher rate of hospitalization in severe UC. Conclusion The management of UC by Italian gastroenterologists in clinical practice is good according to the ECCO consensus recommendations, though some discrepancies are present between GSIBDs and GGs.

https://doi.org/10.1016/j.dld.2018.08.006