6533b828fe1ef96bd1288650
RESEARCH PRODUCT
Granulocytic sarcoma of the oral cavity in a chronic myeloid leukemia patient : an unusual presentation
Paulo-sérgio Da Silva-santosMarina Helena Cury Gallottini MagalhãesBrunno-santos-de Freitas SilvaFabio Luiz CoracinFernanda-paula YamamotoDécio-dos Santos Pinto-juniorsubject
Pathologymedicine.medical_specialtyDiseaseMyelogenousLeukemia Myelogenous Chronic BCR-ABL Positivehemic and lymphatic diseasesBiopsyMedicineHumansSarcoma MyeloidGeneral DentistryAcute leukemiamedicine.diagnostic_testbusiness.industryMyeloid leukemiaMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]LeukemiaOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASSurgeryFemaleMouth NeoplasmsSarcomabusinessInfiltration (medical)description
Intraoral granulocytic sarcoma is an unusual manifestation of chronic or acute leukemia. The oral manifestations often involve enlargements of the gingival and mucosal tissue from direct leukemic cell infiltration. Only 38 cases have been reported in scientific literature to date. We present the case of a 47 year-old female who was diagnosed with chronic myeloid leukemia (CML) in December 2006. She was referred to a dentist for further evaluation, revealing generalized gingival overgrowth as well as periodontal, apical disease, and bleeding of the gums. An oral biopsy was performed and histological features revealed immature blast-like cells.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2009-02-11 |