6533b828fe1ef96bd1288d0b
RESEARCH PRODUCT
A 20-channel receive-only mouse array coil for a 3 T clinical MRI system
Florian M. MeiseBoris KeilJohannes T. HeverhagenLawrence L. WaldLawrence L. WaldChristina TriantafyllouChristina TriantafyllouLaura M. SchreiberGraham C. WigginsKlaus J. Klosesubject
Physicsmedicine.diagnostic_testPreamplifierPhysics::Medical PhysicsWhole body imagingMagnetic resonance imagingequipment and suppliesLow impedanceImaging phantomTransducerNuclear magnetic resonanceElectromagnetic coilArray coilmedicineRadiology Nuclear Medicine and imagingBiomedical engineeringdescription
A 20-channel phased-array coil for MRI of mice has been designed, constructed, and validated with bench measurements and high-resolution accelerated imaging. The technical challenges of designing a small, high density array have been overcome using individual small-diameter coil elements arranged on a cylinder in a hexagonal overlapping design with adjacent low impedance preamplifiers to further decouple the array elements. Signal-to-noise ratio (SNR) and noise amplification in accelerated imaging were simulated and quantitatively evaluated in phantoms and in vivo mouse images. Comparison between the 20-channel mouse array and a length-matched quadrature driven small animal birdcage coil showed an SNR increase at the periphery and in the center of the phantom of 3- and 1.3-fold, respectively. Comparison with a shorter but SNR-optimized birdcage coil (aspect ratio 1:1 and only half mouse coverage) showed an SNR gain of twofold at the edge of the phantom and similar SNR in the center. G-factor measurements indicate that the coil is well suited to acquire highly accelerated images.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2011-03-23 | Magnetic Resonance in Medicine |