6533b828fe1ef96bd1288ef3
RESEARCH PRODUCT
Pancoast's syndrome caused by lymph node metastasis from breast cancer.
Cristina ValdesiMarta PeriMarinella ZilliVincenzo Di Stefanosubject
medicine.medical_specialtypain (palliative care)Settore MED/06 - Oncologia MedicaPhysical examinationBreast Neoplasmspain (neurology)03 medical and health sciencesbreast cancer0302 clinical medicineBreast cancerFatal OutcomeShoulder PainmedicineHumansPain ManagementBrachial PlexusInfraclavicular Lymph NodeZiconotideLungUnusual Presentation of More Common Disease/Injurymedicine.diagnostic_testperipheral nerve diseasebusiness.industryPancoast SyndromeGeneral MedicineMiddle Agedmedicine.diseaseMetastatic breast cancermedicine.anatomical_structure030220 oncology & carcinogenesisLymphatic MetastasisNeuropathic painNeuralgiaSettore MED/26 - NeurologiaFemaleRadiologyLymph NodesbusinessBrachial plexus030217 neurology & neurosurgerymedicine.drugdescription
Pancoast’s syndrome may be the result of neoplastic, inflammatory or infectious disease. We report an unusual case of Pancoast’s syndrome in a patient with metastatic breast cancer. A 54-year-old woman, affected by metastatic breast cancer, presented for severe shoulder pain, paraesthesia and numbness in the right arm. Despite further multiple lines of systemic chemotherapy, she developed a progressive enlargement of retropectoral, supraclavicular and infraclavicular lymph node metastases, which involved brachial plexus, apex of lung and anterior mediastinum. Physical examination revealed severe weakness of proximal muscles of the right arm. Neuropathic pain was managed with pharmacological treatment. Lastly, the patient has been treated with intrathecal analgesia with morphine and ziconotide with a good control of pain. The patient died after 3 months.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2018-11-01 | BMJ case reports |