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RESEARCH PRODUCT

Overview of the Evolution of Silica-Based Chromo-Fluorogenic Nanosensors

Ramón Martínez-máñezBeatriz Lozano-torresFélix SancenónJosé V. Ros-lisLuis Pla

subject

ColorNanoparticleNanotechnologyReviewMesoporous010402 general chemistry01 natural sciencesBiochemistryFluorescencegated materialsAnalytical ChemistryQUIMICA ORGANICAMolecular recognitionsensorNanosensorarraysGated materialsElectrical and Electronic EngineeringArraysInstrumentationSensorchemistry.chemical_classification010405 organic chemistryChemistryChromogenicOligonucleotideBiomoleculeQUIMICA INORGANICASilicaHighly selectiveAtomic and Molecular Physics and Opticscolor0104 chemical sciencessilicaNanoparticlesnanoparticlesfluorescencemolecular recognitionMolecular recognitionmesoporousMesoporous material

description

[EN] This review includes examples of silica-based, chromo-fluorogenic nanosensors with the aim of illustrating the evolution of the discipline in recent decades through relevant research developed in our group. Examples have been grouped according to the sensing strategies. A clear evolution from simply functionalized materials to new protocols involving molecular gates and the use of highly selective biomolecules such as antibodies and oligonucleotides is reported. Some final examples related to the evolution of chromogenic arrays and the possible use of nanoparticles to communicate with other nanoparticles or cells are also included. A total of 64 articles have been summarized, highlighting different sensing mechanisms.

https://doi.org/10.3390/s19235138