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RESEARCH PRODUCT
Biosensors for the determination of SARS-CoV-2 virus and diagnosis of COVID-19 infection
Maryia DrobyshAlmira RamanavicieneRoman ViterChien-fu ChenUrte Samukaite-bubnieneVilma RatautaiteArunas Ramanaviciussubject
QH301-705.5immune complexSARS-CoV-2 virusBiosensing TechniquesReviewCatalysisInorganic Chemistryelectrochemical immunosensorsCOVID-19 TestingHumansSerologic TestsPhysical and Theoretical ChemistryBiology (General)Molecular BiologyQD1-999SpectroscopySARS-CoV-2bioelectrochemistryOrganic ChemistryCOVID-19General MedicineRNA analysisbiosensorsimmobilisation of biomoleculesNanostructuresComputer Science ApplicationsChemistryMolecular Diagnostic Techniquesmolecularly imprinted polymers (MIPs)antigen-antibody interactionCOVID-19 ; SARS-CoV-2 virus ; biosensors ; electrochemical immunosensors ; bioelectrochemistry ; RNA analysis ; antigen-antibody interaction ; immune complex ; immobilisation of biomolecules ; molecularly imprinted polymers (MIPs)description
Monitoring and tracking infection is required in order to reduce the spread of the coronavirus disease 2019 (COVID-19), induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). To achieve this goal, the development and deployment of quick, accurate, and sensitive diagnostic methods are necessary. The determination of the SARS-CoV-2 virus is performed by biosensing devices, which vary according to detection methods and the biomarkers which are inducing/providing an analytical signal. RNA hybridisation, antigen-antibody affinity interaction, and a variety of other biological reactions are commonly used to generate analytical signals that can be precisely detected using electrochemical, electrochemiluminescence, optical, and other methodologies and transducers. Electrochemical biosensors, in particular, correspond to the current trend of bioanalytical process acceleration and simplification. Immunosensors are based on the determination of antigen-antibody interaction, which on some occasions can be determined in a label-free mode with sufficient sensitivity.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2022-01-01 |