6533b829fe1ef96bd128a596

RESEARCH PRODUCT

RELEASE BY SYMPATHETIC STIMULATION OF ALPHA-METHYLNORADRENALINE STORED IN THE HEART AFTER ADMINISTRATION OF ALPHA-METHYLDOPA.

L. MaîtreErich Muscholl

subject

Sympathetic nervous systemmedicine.medical_specialtySerotoninSympathetic Nervous SystemGanglionic BlockersGanglionic BlockadersPiperazinesCellular and Molecular NeuroscienceNorepinephrineCatecholaminesInternal medicinemedicineAnimalsMethyldopaMolecular BiologyNordefrinPharmacologybusiness.industryResearchHeartCell Biologyα methyldopaSympathetic stimulationPerfusionmedicine.anatomical_structureEndocrinologyMolecular MedicineMethyldopaRabbitsbusinessPerfusionSelective Serotonin Reuptake Inhibitorsmedicine.drug

description

Dans les cœurs de lapins traites par l'α-methyldopa, la depletion de la noradrenaline s'accompagne d'une fixation importante d'α-methylnoradrenaline. Sous l'effet de stimulation sympathique ou d'iodure de dimethylphenyl-piperazinium, ces cœurs liberent conjointement de la noradrenaline et de l'α-methylnoradrenaline.

10.1007/bf02151307https://pubmed.ncbi.nlm.nih.gov/14099879