6533b829fe1ef96bd128ac92
RESEARCH PRODUCT
Solid glucose biosensor integrated in a multi-well microplate coupled to a camera-based detector: Application to the multiple analysis of human serum samples
Carmen Molins-leguaJavier Pla-tolósYolanda Moliner-martínezPilar Campíns-falcósubject
Detection limitChromatographyMaterials scienceDetectorRelative standard deviationMetals and Alloys02 engineering and technologyPhotometer010402 general chemistry021001 nanoscience & nanotechnologyCondensed Matter PhysicsSerum samples01 natural sciences0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic Materialslaw.inventionMicroplate ReaderlawMaterials ChemistryElectrical and Electronic Engineering0210 nano-technologyInstrumentationBiosensordescription
Abstract In the present work, a biosensor adapted in a 96-well microplate has been coupled with a smartphone-based photometer in order to develop a low-cost colorimetric multi-sample dispositive. The strength of this biosensing system is based on the integration of the biosensor into the 96-well microplate and the use of a smartphone and free image analysis software as a microplate reader. The performance of the proposed biosensor has been demonstrated to determine glucose in several human serum samples. This method is simple, cost-effective, sensitive and selective for the determination of glucose in serum, with detection limits of 1.8 mg/dL and a good linearity over the range 6–88 mg/dL. Precision was also satisfactory (relative standard deviation, %RSD
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2018-04-01 | Sensors and Actuators B: Chemical |