Thrombo-Inflammation in Cardiovascular Disease

6533b829fe1ef96bd128afb2

RESEARCH PRODUCT

Thrombo-Inflammation in Cardiovascular Disease

E. D'alessandro C. Becker W. Bergmeier C. Bode J.h. Bourne H. Brown H.r. Buller A.j. Ten Cate-hoek V. Ten Cate Y.j.m. Van Cauteren Y.f.h. Cheung A. Cleuren D. Coenen H.j.g.m. Crijns I. De Simone S.c. Dolleman C.e. Klein D.i. Fernandez L. Granneman A.t. Van T Hof P. Henke Y.m.c. Henskens J.n. Huang L.k. Jennings N. Jooss M. Karel D. Van Den Kerkhof F.a. Klok B. Kremers B. Lammle A. Leader A. Lundstrom N. Mackman P.m. Mannucci Z. Maqsood P.e.j. Van Der Meijden M. Van Moorsel L.a. Moran J. Morser M. Van Mourik S. Navarro R.a.i. Neagoe R.h. Olie P. Van Paridon J. Posma I. Provenzale P.h. Reitsma B. Scaf L. Schurgers J. Seelig A. Siegbahn Bob Siegerink O. Soehnlein E.m. Soriano M.a. Sowa H.m.h. Spronk R.f. Storey C. Tantiwong A. Veninga X.q. Wang S.p. Watson J. Weitz S.s. Zeerleder H. Ten Cate B. Lina B. Christoph H. Marc K. Peter K.r. Gregorylip M. Steffen V. Philipp W. Christian W. Johann Sci Reviewer Comm

subject

0301 basic medicine VENOUS THROMBOSIS medicine.medical_specialty pulmonary embolism Neutrophils Ischemia ISCHEMIA-REPERFUSION INJURY Disease 030204 cardiovascular system & hematology CATHETER-DIRECTED THROMBOLYSIS 03 medical and health sciences 0302 clinical medicine PERIPHERAL ARTERY-DISEASE Medicine Animals Humans Platelet Myocardial infarction DEEP-VEIN THROMBOSIS coagulation Intensive care medicine Stroke Blood Coagulation Expert Testimony thrombosis business.industry ACUTE CORONARY SYNDROMES NEUTROPHIL EXTRACELLULAR TRAPS Hematology Neutrophil extracellular traps Venous Thromboembolism ACTIVATABLE FIBRINOLYSIS INHIBITOR medicine.disease Atherosclerosis Thrombosis stroke Immunity Innate 3. Good health Venous thrombosis 030104 developmental biology myocardial infarction TISSUE FACTOR Cardiovascular Diseases inflammation platelets Endothelium Vascular business SUBCLINICAL LEAFLET THROMBOSIS

description

AbstractThrombo-inflammation describes the complex interplay between blood coagulation and inflammation that plays a critical role in cardiovascular diseases. The third Maastricht Consensus Conference on Thrombosis assembled basic, translational, and clinical scientists to discuss the origin and potential consequences of thrombo-inflammation in the etiology, diagnostics, and management of patients with cardiovascular disease, including myocardial infarction, stroke, and peripheral artery disease. This article presents a state-of-the-art reflection of expert opinions and consensus recommendations regarding the following topics: (1) challenges of the endothelial cell barrier; (2) circulating cells and thrombo-inflammation, focused on platelets, neutrophils, and neutrophil extracellular traps; (3) procoagulant mechanisms; (4) arterial vascular changes in atherogenesis; attenuating atherosclerosis and ischemia/reperfusion injury; (5) management of patients with arterial vascular disease; and (6) pathogenesis of venous thrombosis and late consequences of venous thromboembolism.

year	journal	country	edition	language
2020-04-01	Thrombosis and Haemostasis

10.1055/s-0040-1708035 https://cris.maastrichtuniversity.nl/en/publications/4443f5b1-76c4-40ea-baf9-0660bd4223d2