FCγRIIa and FCγRIIIa polymorphisms (SNPs) and cetuximab (C) benefit in the EXPERT-C trial.

6533b82afe1ef96bd128b666

RESEARCH PRODUCT

FCγRIIa and FCγRIIIa polymorphisms (SNPs) and cetuximab (C) benefit in the EXPERT-C trial.

Andrew Wotherspoon Susana Rosello Keranen Clare Peckitt Janet Thomas Ian Chau Gina Brown David Cunningham David Gonzalez De Castro Bengt Glimelius Diana Tait Francesco Sclafani Sanna Hulkki Wilson Jaume Capdevila Ruwaida Begum Jacqueline Oates

subject

Oncology Cancer Research medicine.medical_specialty Cetuximab medicine.drug_class Colorectal cancer business.industry Single-nucleotide polymorphism Bioinformatics Monoclonal antibody medicine.disease digestive system diseases Oncology Internal medicine medicine business medicine.drug

description

3573 Background: FCγRIIa-H131R and FCγRIIIa-V158F SNPs have been reported to enhance the immune-mediated effects of monoclonal antibodies including cetuximab (C) in metastatic colorectal cancer (CR...

year	journal	country	edition	language
2014-05-20	Journal of Clinical Oncology

https://doi.org/10.1200/jco.2014.32.15_suppl.3573

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