6533b82afe1ef96bd128b954

RESEARCH PRODUCT

Physical exercise in the prevention and treatment of Alzheimer's disease

Aitor CarreteroMari Carmen Gomez-cabreraEsther Garcia-dominguezCristina Blasco-lafargaÁNgela G. CorreasGloria Olaso-gonzalezAdrián De La RosaCoralie Arc-chagnaudConsolación García-lucergaFernando MillanJose ViñaAndrea Salvador-pascual

subject

GerontologyAgingPsychological interventionPhysical Therapy Sports Therapy and RehabilitationPhysical exercisetau ProteinsDiseaseReviewLifestyle factorsExercise traininglcsh:GV557-1198.99503 medical and health sciences0302 clinical medicineCognitionAlzheimer DiseaseRisk FactorsmedicineDementiaAerobic exerciseAnimalsHumansOrthopedics and Sports Medicine030212 general & internal medicineHealthy LifestyleNerve Growth Factorslcsh:Sports medicineExerciseAerobic exerciselcsh:SportsInflammationAmyloid beta-Peptidesbusiness.industryMechanism (biology)BrainMultidomain interventionsCognition030229 sport sciencesmedicine.diseaseMental healthResistance exercise3. Good healthExercise TherapyCerebrovascular CirculationDementialcsh:RC1200-1245business[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology

description

Highlights • Low levels of physical activity are a risk factor associated with Alzheimer's disease. • Older adults who exercise are more likely to maintain cognition. • Exercise modulates amyloid β turnover, inflammation, synthesis, and release of neurotrophins, and cerebral blood flow.

10.1016/j.jshs.2020.01.004https://hal.inrae.fr/hal-02529698